3-Hydroxy-2-naphthoic acid hydrazide

Products Category: Rubber Additives

3-Hydroxy-2-naphthoic acid hydrazide is a high-purity (≥99%) organic synthesis intermediate, directly supplied from a reliable China manufacturer with stable inventory and strict quality control. This off-white to light yellow crystalline powder features a melting point of 205-208°C and serves as a versatile building block for pharmaceutical. Factory-direct pricing ensures cost efficiency and fast worldwide delivery from ready stock.Please feel free to contact us for a COA and quotation.
Cas No.:5341-58-2
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Technical Documentation
Available upon request
Contact us to receive SDS, COA and TDS documents for this product.
01

Product Name

Identification & Synonyms

Product Name: 3-Hydroxy-2-naphthoic acid hydrazide

Product Alias:

3-Hydroxy-2-naphthoic Acid Hydrazide   |   2-Naphthalenecarboxylic acid, 3-hydroxy-, hydrazide   |   2-Hydroxy-3-naphthoic Acid Hydrazide   |   3-Hydroxy-2-naphthohydrazide   |   3-hydroxynaphthalene-2-carbohydrazide

02

Product Description

Specifications & Quality Standards

CAS No.: 5341-58-2

Molecular Formula: C₁₁H₁₀N₂O₂

Molecular Weight: 202.21 g/mol

EINECS No.: 226-282-7

MDL No.: MFCD00004097

Appearance: White to orange to green powder to crystalline solid

Purity: ≥ 98.0% (by Titration)

Melting Point: 205 – 211°C (literature: 205-208°C , 208°C , 209-211°C )

Boiling Point: Not available

Density: 1.352 g/cm³ (predicted)

Solubility: Soluble in hot benzene and ethanol; Insoluble in water 

03

Application

Industry Applications & Advantages

3-Hydroxy-2-naphthoic acid hydrazideis primarily used as a key intermediate in pharmaceutical synthesis, particularly for the preparation of 1,3,4-thiadiazole derivatives, hydrazone compounds, and thiazolidinone derivatives with potential antimicrobial, antioxidant, anti-inflammatory, and anticancer activities . It also serves as an effective chemosensor for the fluorescent detection of cyanide (CN) and aluminum ions (Al³⁺) in food and pharmaceutical samples, with detection limits as low as 0.8 µM and 1.9 µM respectively . Additionally, it functions as a reactive matrix for MALDI-MS detection of steroids with carbonyl groups in biological samples, and can be used for the synthesis of disperse dyes for polyester fabrics.

Our Advantages:We achieve 100% self-sufficiency in raw materials for the benzophenone series, with a domestic market share of over 60%. We hold valid domestic production licenses to ensure stable and compliant supply. We offer products in quantities ranging from tonnage to kilogram scale, and all products comply with GMP and ICH Q7 guidelines.
04

Packaging & Storage

Handling, Storage & Logistics

Packaging: 25kg high-pressure fiber drum

Storage Conditions: Keep container tightly sealed, place in an airtight container, and store in a cool and dry place.

Stability: Stable under normal temperature and pressure. Avoid contact with oxidizing agents.

Finished Products Warehouse
Finished Products Warehouse
Loading of Products
Loading of Products
Loading & Warehouse Outbound Delivery
Loading & Warehouse Outbound Delivery
Order Ex-factory
Order Ex-factory
05

Safety Information

GHS Classification & Regulatory Data

Symbol


GHS07

Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Personal Protective Equipment

dust mask type N95 (US);Eyeshields;Gloves

Hazard Codes

Xi,C

Risk Phrases

R36/37/38

Safety Phrases

S26-S36

RIDADR

NONH for all modes of transport

WGK Germany

3

HS Code

2928000090

06

Factory Display

Production Capacity & Facilities

Looking for a reliable 3-Hydroxy-2-naphthoic acid hydrazide supplier?

Ruikaixing (Hubei Reaction Technology Co., Ltd.) is your partner. We hold China's legal benzilic acid production license – one of the few certified producers. 100% raw material self-sufficiency for benzophenone series, with >60% domestic market share. Stable and trustworthy.

Our state-level industrial park facility includes factory gates, production areas and Class A workshops with full supporting infrastructure.

Factory gateFactory gate
Production plant areaProduction plant area
Workshop No.1Workshop No.1
Workshop 2Workshop 2

We has two Class A production workshops with installed equipment, mainly producing pharmaceutical intermediates. It is equipped with 50 reaction vessels and related ancillary equipment, which can carry out various organic synthesis reactions. The planned annual production capacity is 2000 tons and the output value is 200 million yuan; The instruments for water supply, heating, cooling, and power supply are fully equipped with gas and equipped with an automated control system.

Inside the workshop and supporting warehouseInside the workshop and supporting warehouse
Inside the workshop and supporting warehouseInside the workshop and supporting warehouse
Inside the workshop and supporting warehouseInside the workshop and supporting warehouse
Inside the workshop and supporting warehouseInside the workshop and supporting warehouse

Reaction has complete testing equipment, including 3 high-performance liquid chromatographs (HPLC), 1 gas chromatograph (GC), a moisture analyzer, a turbidity meter, a spectrophotometer, a melting point apparatus, and other testing devices. The laboratory covers an area of 100 square meters with fully equipped facilities, enabling research and development related to fine chemical products.

Experimental StudioExperimental Studio
Inspection StudioInspection Studio
07

Certifications

Patents, Qualifications & Partnerships

9 invention patents and 7 utility model patents covering synthesis processes, raw material ratios, production workflows and equipment improvements. Collaborations with Wuhan University of Technology, Wuhan University of Science and Technology, and Hubei University.

Certification
Certification
Certification
Certification
Certification
Certification
Certification
Certification
08

Environmental Protection and Safety Facilities

Patents, Qualifications & Partnerships

The production equipment is equipped with a complete set of DCS control system, and all unit reactions can be completed in the control room, avoiding the randomness of personnel operations and ensuring the safety of production personnel while improving production quality.

Control Room Monitoring
Control Room Monitoring
Automation Control System
Automation Control System

According to the requirements of the environmental protection and safety departments, the company has established a daily treatment device for 30 tons of sewage and a VOC absorption device for tail gas. It has also built an accident emergency pool, a fire water station, a primary rainwater pool, a sewage monitoring pool, and a sewage online monitoring room. The sewage online has been verified by the State Grid platform.

Wastewater Treatment Area
Wastewater Treatment Area
Wastewater Treatment Station
Wastewater Treatment Station
Exhaust Gas Absorption System
Exhaust Gas Absorption System
09

Reaction Team

Patents, Qualifications & Partnerships
Reaction Team
Reaction Team
Reaction Team
10

FAQ

Frequently Asked Questions
Q1: Is Reaction a manufacturer or a trading company?
A:

Hubei Reaction Technology Co., Ltd. is a professional manufacturer established in 2014 with a total investment of 36 million RMB. Our production base is located in the state-level Saifu Industrial Park in Yingcheng City, Hubei Province.

Q2: Do you have quality certifications?
A:

Yes. We passed ISO 9001 Quality Management System certification in 2015, covering every step from procurement, production, packaging to transportation.

Q3: Do you offer custom synthesis / OEM services?
A:

Yes. Our technical team includes experienced engineers and professors with strong R&D capabilities. We can develop custom products according to your specifications.

Q4: What is your typical lead time?
A:

Lead time depends on the product and order quantity. Generally, for standard products with stock, delivery can be made within 7–15 days after receiving the deposit. For custom products or large quantities, production typically takes 15–30 days. We will provide a confirmed delivery schedule upon order confirmation and keep you informed throughout the process.

Q5: What documentation do you provide for customs clearance?
A:

We provide a complete set of export documents to facilitate smooth customs clearance at your destination:

  • Commercial Invoice
  • Packing List
  • Bill of Lading (B/L)
  • Certificate of Origin (if required)
  • MSDS (Material Safety Data Sheet)
  • Certificate of Analysis (CoA)
  • Other special documents as required by your local customs
Q6: Do you have an environmental policy?
A:

Yes. Our production base is located in a nationally certified chemical industrial park, and we were among the first enterprises in the park to receive environmental approval. We adhere to green manufacturing principles and sustainable practices throughout our operations.

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